I also love to see each card as a peice of art, but transposing independent art onto the card itself is kind of overlooking the fact that it is, in fact, playing cards. Transformation decks, for example, usually incorporate the cards elements IN the design. In this case, it's almost literally an art book printed on cards rather than actual pages. Not to mention the standard rider backs.
I would buy one if I had a particular interest in the artist's work. If for example there was a deck printed with Tim Burton's art on it(Which I think there is, actually), I'd be more likely to buy it because I like Tim Burton's work, but others might not be interested because it would have more in common with an art book than a deck of cards.
Then again, I'm not that hardcore of a collector. If I was, chances are I'd buy it anyway, for the sake of my collection being complete.